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In regard to pre-builds my current observation is construction of an unimpeded save file to start a game. Once the prebuilt process is complete then, layer on everything else.
Doing it at the vault exit still is valid, I just see less confusion, more stability, less glitches in the selection process, a smoother and fewer conflicts while prebuilt are running, and potential time savings with a pure pre built save file before other mods are installed.
all this said, I also believe if doing it this way that level 3 is the way to go. Thus good not to have other mods running to muck that process up.