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Add the following to your Fallout4custom.ini:
fExtraTaskletBudgetMS=2.4
fUpdateBudgetMS=2.4
iMaxAllocatedMemoryBytes=307200
iMaxMemoryPageSize=1024
iMinMemoryPageSize=256
Also, are you running any combat related mods like Pack Attack?
I'm almost 60 hours in to a game with all the above as well as the new Depravity mod by the same team. Only issues so far have been related to PANPC, but running some tests on Greslins new patch yesterday, it seems he has all but eliminated the stack dump issue when running it along side...